QUESTION 1 What are some potential indications for the long term use of acid-su

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QUESTION 1
What are some potential indications for the long term use of acid-suppressive therapy and given the above potential adverse events, what would your discussion entail for a patient, who through mutual decision making, is considering long term therapy with a PPI?
QUESTION 2
H. pylori infection causes gastritis, PUD, gastric cancer and mucosa-associated lymphoid tissue (MALT) lymphoma. Approximately 20% of infected individuals will develop PUD and less than 1% will develop gastric cancer. HP eradication markedly decreases ulcer recurrence. Assuming your patient tests positive for this organism, describe your therapeutic plan including possible medication options, patient and drug related factors used to make your selection, duration of therapy, monitoring, patient education and any potential follow up such as labs, testing or continued use for PPIs.
QUESTION 3
A 64-year-old, Latin female patient was referred to your Clinic for gastroesophageal reflux disease (GERD) management after cardiac issues were ruled out. She has difficulty sleeping because of a burning feeling in chest at night which wakes her up. She notices more severe symptoms on the weekends. She is married and lives with her husband (a retired engineer) of 40 years. She and her husband have two sons, aged 37 and 35. She served in the Army for six years. She works as a legal assistant for law firm. She Smokes 5 cigarettes per day ( down from 1 ppd 2 years ago) and has 2-3 drinks on weekends, especially beer with dinner from the food trucks.
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What typical and atypical symptoms of GERD does the patient have?
Which of the patient’s lifestyle and medications can make the GERD symptoms worse?
Which of the patient’s medications decrease lower esophageal sphincter pressure?
What is the drug of choice for the patient’s acid suppression therapy, and how long should the patient be treated?
Please provide answers to each question in a minimum of 250 words. Refer to at least two sources (one from a test book and the other from a peer review article) and in APA format

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